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The earlier section of these notes on reducing errors and variation in epidemiological measurements touches briefly on the challenges of using observational techniques and the importance of assessing validity.

The purposes of this article are to present a brief introduction to the concept of test method validation, to describe basic methods of validation, and to provide the clinician with a sense of the importance of test validation with respect to nonconventional species.

The researcher in defining variables should be aware of the need for circumspection in use of contentious terms such as ‘race’ (see Terminology section) and to recognize the dynamic nature of ethnicity-related concepts, as well as the socio-political contexts in which they are developed.“This will ensure the scientific validity of the research question and will allow research findings to be evaluated within the context of continuously changing scientific and societal conceptions of these definitions” (Fisher, Hoagwood, Boyce, Duster, Frank, Grisso, Levine, Macklin, Spencer, Takanishi, Trimble, & Zayas 2002; Fisher & Wallace 2000).

Most published North American studies base their measures of diversity on categories of race but, as Fuller (Fuller 2003) notes, lumping together into a group large numbers of individuals who share little in terms of phenotype, culture, and/or behaviour inhibits reaching appropriate solutions, with progress being made when the issue of health disparities is reframed as one of phenotype/environmental mismatch. 2004) quantified misclassification of birthplace data for Asian cancer patients in the Greater Bay Area Cancer Registry in northern California by comparing registry birthplace information with self-reported birthplace from interview, and then identified sociodemographic and hospital characteristics associated with birthplace completeness and misclassification. Among US-born Asians, those misclassified as foreign-born were more likely than those correctly classified to prefer a non-English primary language.

Researchers chose which type of instrument, or instruments, to use based on the research question.

Examples are listed below: is the extent to which an instrument measures what it is supposed to measure and performs as it is designed to perform.

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